8 publications across the model–experiment loop. Explore by stage.

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2026 new
Journal article

Fabrication of bioprints self-coated with thermally sensitive lactobacilli for CAUTI applications

Caden Maners, Anthony J. Kyser, Davis Verhoeven, Bassam Fotouh, Arielle Greiner, Nicole M. Gilbert, Hermann B. Frieboes

European Journal of Pharmaceutics and Biopharmaceutics 221, 114993

Catheter-associated urinary tract infections (CAUTI) represent a large healthcare burden, accounting for a substantial portion of hospital-acquired infections in the United States.

Fabricate CAUTI
DOI ↗ cited by 0
2025 cited 8
Journal article FIRST AUTHOR

Drug and therapeutic intravaginal delivery targeting diseases in the female reproductive tract: A mathematical modeling perspective

Bassam Fotouh, Anthony J. Kyser, Hermann B. Frieboes

Journal of Controlled Release 384, 113924

Intravaginal drug and therapeutic delivery targeting diseases in the female reproductive tract is advantageous, yet presents significant challenges due to unique anatomical features, cyclic…

Model Bacterial vaginosis
DOI ↗ cited by 8
2025 cited 6
Journal article FIRST AUTHOR

Dual probiotic and antibiotic therapy targeting bacterial vaginosis: An integrated experimental/computational modeling perspective

Bassam Fotouh, Anthony J. Kyser, Mohamed Y. Mahmoud, Hermann B. Frieboes

Biomedical Engineering Advances 9, 100163

A novel strategy delivering both metronidazole and L. crispatus via 3D-printed scaffolds was recently shown to target pathogens in bacterial vaginosis (BV) while promoting beneficial…

ModelDesign Bacterial vaginosis
DOI ↗ cited by 6
2025 cited 7
Journal article

Electrospun nanofibers: Focus on local therapeutic delivery targeting infectious disease

Anthony J. Kyser, Bassam Fotouh, Victoria Harris, Rudra Patel, Caden Maners, Hermann B. Frieboes

Journal of Drug Delivery Science and Technology 104, 106520

Whether it be due to genetic variances, lack of patient adherence, or sub-optimal drug metabolism, the risk of antibiotic resistance from medications administered systemically continues to…

Fabricate
DOI ↗ cited by 7
2024 cited 4
Journal article

Sustained dual delivery of metronidazole and viable Lactobacillus crispatus from 3D-printed silicone shells

Anthony J. Kyser, Mohamed Y. Mahmoud, Bassam Fotouh, Rudra Patel, Christy Armstrong, Marnie Aagard, Isaiah Rush, Warren Lewis, Amanda Lewis, Hermann B. Frieboes

Biomaterials Advances 165, 214005

Bacterial vaginosis (BV) is an imbalance of the vaginal microbiome in which there are limited lactobacilli and an overgrowth of anaerobic and fastidious bacteria such as Gardnerella.

FabricateTest Bacterial vaginosis
DOI ↗ cited by 4
2023 cited 14
Journal article

Development and Characterization of Lactobacillus rhamnosus-Containing Bioprints for Application to Catheter-Associated Urinary Tract Infections

Anthony J. Kyser, Mohamed Y. Mahmoud, Nicholas T. Johnson, Bassam Fotouh, Jill M. Steinbach-Rankins, Nicole M. Gilbert, Hermann B. Frieboes

ACS Biomaterials Science & Engineering 9(7), 4277–4287

Catheter-associated urinary tract infections (CAUTI) are a significant healthcare burden affecting millions of patients annually.

Fabricate CAUTI
DOI ↗ cited by 14

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